Search Word(s) in Title, Keywords, Authors, and Abstract: Yi Pan

Deep Learning in Genomic and Medical Image Data Analysis: Challenges and Approaches
Ning Yu, Zeng Yu, Feng Gu, Tianrui Li, Xinmin Tian and Yi Pan
Page: 204~214, Vol. 13, No.2, 2017
10.3745/JIPS.04.0029
Keywords: Bioinformatics, Deep Learning, Deep Neural Networks, DNA Genome Analysis, Image Data Analysis, Machine Learning, lincRNA
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Artificial intelligence, especially deep learning technology, is penetrating the majority of research areas, including the field of bioinformatics. However, deep learning has some limitations, such as the complexity of parameter tuning, architecture design, and so forth. In this study, we analyze these issues and challenges in regards to its applications in bioinformatics, particularly genomic analysis and medical image analytics, and give the corresponding approaches and solutions. Although these solutions are mostly rule of thumb, they can effectively handle the issues connected to training learning machines. As such, we explore the tendency of deep learning technology by examining several directions, such as automation, scalability, individuality, mobility, integration, and intelligence warehousing.


A Comprehensive Review of Emerging Computational Methods for Gene Identification
Ning Yu, Zeng Yu, Bing Li, Feng Gu and Yi Pan
Page: 1~34, Vol. 12, No.1, 2016
10.3745/JIPS.04.0023
Keywords: Cloud Computing, Comparative Methods, Deep Learning, Fourier Transform, Gene Identification, Gene Prediction, Hidden Markov Model, Machine Learning, Protein-Coding Region, Support Vector Machine
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Gene identification is at the center of genomic studies. Although the first phase of the Encyclopedia of DNA Elements (ENCODE) project has been claimed to be complete, the annotation of the functional elements is far from being so. Computational methods in gene identification continue to play important roles in this area and other relevant issues. So far, a lot of work has been performed on this area, and a plethora of computational methods and avenues have been developed. Many review papers have summarized these methods and other related work. However, most of them focus on the methodologies from a particular aspect or perspective. Different from these existing bodies of research, this paper aims to comprehensively summarize the mainstream computational methods in gene identification and tries to provide a short but concise technical reference for future studies. Moreover, this review sheds light on the emerging trends and cutting-edge techniques that are believed to be capable of leading the research on this field in the future.